Pulmonary circulation and ventilation

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Pulmonary circulation and ventilation.

The pulmonary circuit receives the whole of the cardiac output, and the flow through it is governed by events in the systemic circulation. Its function is gaseous exchange, and the low resistance and high capacitance of the circuit is subservient to this function. Local flow is affected by intra-alveolar oxygen tensions and regional flow by passive hydrostatic effects due to gravity. The distri...

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Pulmonary Circulation and the Ventilation- Perfusion Ratio

The heart drives two separate and distinct circulatory systems in the body: the pulmonary circulation and the systemic circulation. The pulmonary circulation is analogous to the entire systemic circulation. Similar to the systemic circulation, the pulmonary circulation receives all of the cardiac output. Therefore, the pulmonary circulation is not a regional circulation like the renal, hepatic,...

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Fetal and neonatal pulmonary circulation.

During fetal life, gas exchange is carried out in the placenta. The lung does not have a physiological role, apart from possible metabolic functions which include secretion of hormones, enzymatic conversion of inactive substances to functional hormones, and degradation of active materials to inactive metabolites. Blood flow through the lungs is quite low during fetal life; most of the systemic ...

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Diabetes and the pulmonary circulation.

DIABETES IS AN EPIDEMIC in the United States, affecting 8% of the population. The hallmark of diabetes is hyperglycemia due to either insulin deficiency or insulin resistance. Systemic vascular dysfunction is a central part of the pathophysiology of both type I insulin-dependent and type II non-insulin-dependent diabetes and involves both the microand macrocirculation (11). Coronary heart disea...

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Fulvine and the pulmonary circulation.

The pyrrolizidine alkaloid, fulvine, is now accepted as a major cause of veno-occlusive disease of the liver in the West Indies, where it is ingested as a decoction of the plant Crotalaria fulva in bush tea. Fulvine is similar in chemical structure to monocrotaline, which is known to cause pulmonary hypertension in rats. Thirty young female rats were given a single dose of fulvine either by int...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1974

ISSN: 0032-5473

DOI: 10.1136/pgmj.50.587.562